Scientists from the world’s largest beauty firms have tested new approach methodologies (NAMs) to assess skin sensitisation on several new cosmetic-relevant substances, demonstrating promise but highlighting hurdles industry still needs to overcome.
The publication of defined approaches to in silico skin sensitisation chemical assessment is a landmark moment for the Organisation for Economic Co-operation and Development (OECD) with significant implications for an animal-free future, say agency leaders.
The European Chemicals Agency (ECHA) has published advice on how industry can reliably combine non-animal data from different sources to assess skin sensitisation of chemicals in the EU, using the new Organisation for Economic Co-operation and Development...
An animal-free testing strategy for predicting skin sensitisation and allergen potency co-developed by chemistry major BASF and fragrance and flavour specialist Givaudan has been approved by the Organisation for Economic Co-operation and Development (OECD),...
Fragrance suppliers and finished product manufacturers will have to collaborate closely on reformulation to align with updates on skin sensitisation and aggregate exposure under the International Fragrance Association (IFRA) standards.
![Scientists from Beiersdorf, Chanel, Estée Lauder, Henkel, Kao, L’Oréal, LVMH, Pierre Fabre, Procter & Gamble, Shiseido, Unilever have tested New Approach Methodologies (NAMs) for skin sensitisation on new substances [Getty Images]](/var/wrbm_gb_food_pharma/storage/images/_aliases/news_teaser_medium/publications/cosmetics/cosmeticsdesign-europe.com/headlines/formulation-science/skin-sensitisation-testing-with-new-approach-methodologies-nams-requires-deeper-understanding/15673032-1-eng-GB/Skin-sensitisation-testing-with-New-Approach-Methodologies-NAMs-requires-deeper-understanding.jpg)
![The OECD's guideline on in silico defined approaches to assess skin sensitisation is being praised as a landmark achievement [Getty Images]](/var/wrbm_gb_food_pharma/storage/images/_aliases/news_teaser_medium/publications/cosmetics/cosmeticsdesign-europe.com/headlines/regulation-safety/oecd-skin-sensitisation-defined-approaches-guideline-a-landmark-in-animal-free-future/12998689-1-eng-GB/OECD-skin-sensitisation-defined-approaches-guideline-a-landmark-in-animal-free-future.jpg)
![The OECD guideline outlines defined approaches for skin sensitisation assessment using in silico (computer simulation) methods and wider application under REACH will advance use of non-animal test methods, according to ECHA [Getty Images]](/var/wrbm_gb_food_pharma/storage/images/_aliases/news_teaser_medium/publications/cosmetics/cosmeticsdesign-europe.com/article/2021/10/13/echa-advice-on-oecd-non-animal-skin-sensitisation-assessment-to-help-apply-under-eu-reach-regulation/12922059-1-eng-GB/ECHA-advice-on-OECD-non-animal-skin-sensitisation-assessment-to-help-apply-under-EU-REACH-regulation.jpg)
![The approved approach involves a three-step method for assessing skin sensitisation and a bolt-on test to predict allergen potency [Getty Images]](/var/wrbm_gb_food_pharma/storage/images/_aliases/news_teaser_medium/publications/cosmetics/cosmeticsdesign-europe.com/article/2021/06/30/animal-free-testing-for-skin-sensitisation-allergen-potency-from-basf-and-givaudan-receives-oecd-approval/12607502-1-eng-GB/Animal-free-testing-for-skin-sensitisation-allergen-potency-from-BASF-and-Givaudan-receives-OECD-approval.jpg)
