Alternatives to animal testing for next generation ingredients

By Lucy Whitehouse contact

- Last updated on GMT

Alternatives to animal testing for next generation ingredients

Related tags: Open academy, In vivo

Ahead of a new Open Academy for the industry in Europe, we caught up with one of the speakers on alternative testing methods.

Des Cave, of BioReliance UK, is set to present on the topic during the upcoming Open Academy, due to be held in October in Barcelona, Spain and organised by the Cosmetics Consultants Europe industry association.

Three key alternatives to explore

Cave explains that genetic toxicity is a key area of focus for testing, and alternatives to animal testing have been in high demand since the practice was outlawed across Europe in 2013.

The testing of cosmetics for genetic toxicity is a critical part of the safety testing of cosmetics and ingredients​,” Cave confirms.

A positive in an in vitro genetic toxicology assay is normally followed up by an in vivo assay. This cannot be performed for cosmetics and so other more complex in vitro assays have been developed to overcome this.”

Cave lists the following three alternative models for testing as the key options for cosmetics formulators now and moving forward to the coming period:

  1. 3D Skin Micronucleus assay
  2. 3D Skin comet assay
  3. CANMultiflow assay

In Cave’s presentation at the CCE event, all of these assays will be discussed and explains, with special focus on their advantages and challenges, why and when to use them, and how they fit into the regulatory environment.

About the CCE Open Academy event

Set to take place in Barcelona, Spain, the Open Academy will see a series of eminent experts from across the industry Europe present on various hot topics.

The event spans one day, Monday 16th October, and includes sessions for networking alongside the extensive conference programme.

Highlights include presentations on non-animal testing methods for next generation ingredients, software tools for formulation and regulatory affairs, and CPR, REACH and Brexit. Futher information can be found here.

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