Sirona Biochem compound posts positive anti-ageing results


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Sirona Biochem compound posts positive anti-ageing results

Related tags Stem cell European union Ultraviolet

Cosmetics ingredient and drug discovery firm Sirona Biochem announces that its French partner, Biogalenys, has made an important anti-ageing discovery after one of its compounds came though testing with flying colours.

The effects of Sirona’s glycoprotein SBM-TFC-837 on human fibroblasts came out positive in preliminary, in vitro, studies in response to the stressed condition of ultraviolet (UV) radiation.

The studies showed that cells treated with the Sirona ingredient had a dramatic increase in percent cell viability over time, suggesting the glycoprotein plays an important role in protection against UV induced cell death.

“These results are tremendously exciting and further add to our previously reported results which demonstrated that our glycoproteins were protective against extreme conditions,”​ says Attila Hajdu, Chief Business Development officer of Sirona Biochem.

“We have added this new data to our existing patent and have recently generated significant interest from major pharmaceutical companies that recognize the value that our fluorination platform technology provides.”


According to the company, further studies are ongoing and will continue to assess cell stressors and viability.

The main use for the compounds is in anti-ageing cosmetic products since 80% of visible ageing is directly related to cell death.

Other applications also include cryopreservation, regenerative and protective cosmetic or pharmaceutical products for healing, sunscreens, regenerative and preservative products for preservation of stem cells, and as a preservative for vaccines.

Market focus

The global anti-ageing market is forecast to reach up to $345.8 billion in 2018 from $249.3 billion in 2012.

The related market for regenerative medicine, which aims to restore functional ability to tissues and organs, is set to hit $67.6 billion US in 2020.

The anti-ageing project is supported by Bpifrance and the region Haute Normandie.

Previous projects

The news comes only weeks after Sirona Biochem announced the successful development of a third innovative skin lightening compound that has superior safety, with zero hydroquinone release and 8 times the efficacy of deoxyarbutin.

This innovation was made possible through Sirona’s platform technology of fluorination chemistry and through support of the European Union and the European Regional Development Fund (E.R.D.F.).

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